In men: eunucoidism, climacterium, impotence or androgen deficiency sterility. Post-pubertal cryptorchidia with hypogonadism. As adjuvant medication in states of protein deficiency (convalescence, postoperative, osteoporosis, non-consolidating fractures, cirrhosis, aplastic anemia).
In women: selected cases of climacteric disorder, dysmenorrheal, functional uterine bleeding, chronic mastitis. To prevent painful swelling of the breasts and to suppress lactation. As palliative treatment in progressive breast cancer and endometrial cancer.
Natural androgenic hormone controls the development of male and female sexual organs. In small doses stimulates spermatogenesis, in high doses deprives spermatogenesis and ovarian activity (by inhibiting the pituitary gland). Favors protein anabolism and hydrosaline retention.
Testosterone is contraindicated in case of specific allergy, prostate cancer and breast cancer in men (known or suspected). Do not take during pregnancy and lactation. Caution in asthenic, elderly, hypertensive, renal and epileptic patients. With prudence in young boys. It is not used in women except for indications.
Drug interactions: Barbiturates (especially phenobarbital) and phenylbutazone diminish the effectiveness of testosterone (accelerates metabolic inactivation). Testosterone increases the effect and risk of toxic reactions for coumarin anticoagulants (the dose is reduced by about 25%) and for anti diabetic sulphamides.
In men, high doses and long-term treatment can cause excessive psychomotor stimulation, priapism (discontinuation of treatment), oligospermia. In boys premature closure of epiphyses can occur by stopping growth and early sexual development. Women may experience virilisation, gynecomastia, increased libido and menstrual disorders. Long-term treatment with high doses may be the cause of hypocalcaemia (especially in the course of metastatic breast cancer) and retention of hirosaline. Rarely allergic skin rash, very rarely anaphylactic reactions.
Testosterone does not have a good reputation; its involvement in violent and risky behavior is known. Moreover, some research suggests that dietary supplements of this nature can cause cancer and blood clots. At the same time, testosterone supplements may favor polycythemia, a disease characterized by an abnormal number of red blood cells that can cause heart attacks and strokes, and statistics show that men who follow hormone therapy with testosterone are four times as likely to suffer from this problem.
Some side effects can be caused by buying non-prescription testosterone, so the body might just be responding to the wrong doses that have been administered or the pre-existing diseases that some suffer.